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Nonstop Destinations

Nonstops from Des Moines International Airport (DSM) include many of the nation’s most popular destinations.  Book today and Fly DSM.  

Destinations may be seasonal routes for nonstop service, check with the airlines to book your travel. 

NOTICE: Nonstop service has been impacted by the coronavirus pandemic.  Please visit your airline website for updated nonstop service from DSM. 

Download/Print Map

image of a markerClick on bubble for city, airport and airline information 

ATL - ATLANTA Hartsfield-Jackson International Airport (ATL) Delta Airlines
AUS - AUSTIN Austin-Bergstrom International Airport (AUS) Allegiant Air
AZA - PHOENIX-MESA Phoenix-Mesa Gateway Airport (AZA) Allegiant Air
BNA - NASHVILLE Nashville International Airport (BNA) Allegiant Air
CLT - CHARLOTTE Charlotte Douglas International Airport (CLT) American Airlines
DCA - WASHINGTON D.C. Ronald Reagan Washington National Airport (DCA) American Airlines
DEN - DENVER Denver International Airport (DEN) Frontier Airlines | Southwest Airlines | United Airlines
DFW - DALLAS Dallas Ft. Worth International Airport (DFW) American Airlines
DTW - DETROIT Detroit Metro Airport (DTW) Delta Airlines
IAH - HOUSTON George Bush Intercontinental Airport (IAH) United Airlines
LAS - LAS VEGAS Las Vegas-McCarran International Airport (LAS) Allegiant Air | Frontier Airlines | Southwest Airlines
LAX - LOS ANGELES Los Angeles International (LAX) Allegiant Air
LGA - NEW YORK CITY LaGuardia Airport (LGA) Delta Airlines
MCO - ORLANDO Orlando International Airport (MCO) Frontier Airlines
MDW - CHICAGO Chicago Midway International Airport (MDW) Allegiant Air
MEM - MEMPHIS Memphis International Airport (MEM) Allegiant Air
MIA - MIAMI Miami International Airport (MIA) American Airlines
MSP - MINNEAPOLIS Minneapolis-St. Paul International Airport (MSP) Delta Airlines
ORD - CHICAGO (O'HARE) Chicago's O'Hare International Airport (ORD) American Airlines | United Airlines
PGD - PUNTA GORDA Punta Gorda Airport (PGD) Allegiant Air
PHL - PHILADELPHIA Philadelphia International Airport (PHL) American Airlines
PHX - PHOENIX Phoenix Sky Harbor International Airport (PHX) American Airlines | Frontier Airlines | Southwest Airlines
PIE - TAMPA BAY-ST. PETERSBURG St. Petersburg-Clearwater International Airport (PIE) Allegiant Air
SFB - ORLANDO Orlando Sanford International Airport (SFB) Allegiant Air
SLC - SALT LAKE CITY Salt Lake City International (SLC) Delta Airlines
SRQ - SARASOTA-BRADENTON Sarasota-Bradenton International (SRQ) Allegiant Air
STL - ST. LOUIS Lambert-St. Louis International Airport (STL) Southwest Airlines
VPS - EGLIN AFB Destin-Fort Walton Beach Airport (VPS) (VPS) Allegiant Air